Laurie S W, Wilson K L, Kernahan D A, Bauer B S, Vistnes L M
Ann Plast Surg. 1984 Sep;13(3):191-4. doi: 10.1097/00000637-198409000-00003.
This experimental study in the rabbit establishes a reliable model for the production of skin necrosis analogous to intravenous extravasation injuries in humans. The effectiveness of hyaluronidase in reducing the extent of tissue injury is examined, using several different toxic agents.
这项针对兔子的实验研究建立了一个可靠的模型,用于制造类似于人类静脉外渗损伤的皮肤坏死。使用几种不同的毒性剂,研究了透明质酸酶在减轻组织损伤程度方面的有效性。