Pavie A, Fontanel M, Gandjbakhch I, Bors V, Zargouni N, Jault F, Cabrol C
Ann Cardiol Angeiol (Paris). 1984 Oct;33(6):367-72.
Open heart surgery after 65 is more and more frequent (16% of our surgical cases). Between January 1971 and December 1982, 8 425 open heart operations were performed in this Department, 1 377 of them in patients over 65. Most were cases of aortic valvulitis (620), and calcific aortic stenosis in particular, but also dystrophic aortic insufficiency; 217 patients underwent surgery for mitral valvulitis (rheumatic or dystrophic in origin) and 84 for involvement of more than one valve. Of the 2 440 patients with coronary lesions who underwent surgery, 255 were over 65; beyond this age, a higher rate of association between coronary lesions and valvular disease was found (167 patients undergoing surgery). Surgical mortality (during the first postoperative month) was higher after 65: 11.1% in patients with valve disease, and 11.4% in those with coronary artery disease, whereas in patients under 65 the figures were 6.5% and 4% respectively. On the other hand, in those undergoing surgery for combined valve and coronary disease, mortality over 65 was hardly any higher than under 65 (13.7% as against 10.4%). This justifies screening for coronary artery disease in any candidate for valve surgery aged over 65. These results were achieved thanks to some technical and anaesthetic precautions, and though they may be less satisfactory than those for younger patients, they justify such surgery for all lesions that threaten survival in the short term.
65岁以上患者进行心脏直视手术的情况越来越常见(占我们手术病例的16%)。1971年1月至1982年12月期间,该科室共进行了8425例心脏直视手术,其中1377例患者年龄超过65岁。大多数病例为主动脉瓣炎(620例),尤其是钙化性主动脉瓣狭窄,但也有营养不良性主动脉瓣关闭不全;217例患者因二尖瓣炎(风湿性或营养不良性)接受手术,84例因多个瓣膜受累接受手术。在接受手术的2440例有冠状动脉病变的患者中,255例年龄超过65岁;超过这个年龄,发现冠状动脉病变与瓣膜疾病的关联率更高(167例接受手术)。手术死亡率(术后第一个月内)在65岁以上患者中更高:瓣膜疾病患者为11.1%,冠状动脉疾病患者为11.4%,而65岁以下患者的相应数字分别为6.5%和4%。另一方面,在接受瓣膜和冠状动脉联合疾病手术的患者中,65岁以上患者的死亡率几乎不比65岁以下患者高(分别为13.7%和10.4%)。这证明对任何65岁以上的瓣膜手术候选者进行冠状动脉疾病筛查是合理的。这些结果得益于一些技术和麻醉方面的预防措施,尽管它们可能不如年轻患者的结果令人满意,但它们证明对所有威胁短期生存的病变进行此类手术是合理的。