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[80岁以上患者的心脏手术。51例患者的系列经验]

[Cardiac surgery in patients over 80 years of age. Experience of a series of 51 patients].

作者信息

Nataf P, Gandjbakhch I, Pavie A, Fontanel M, Bors V, Leger P, Vaissier E, Cabrol C

机构信息

Service de chirurgie thoracique et cardio-vasculaire, Hôpital de la Pitié, Paris.

出版信息

Arch Mal Coeur Vaiss. 1990 Mar;83(3):337-41.

PMID:2108627
Abstract

Between January 1980 and June 1988, 51 patients over 80 years of age underwent open heart surgery at the La Pitié hospital (26 women and 25 men; average age 82 +/- 2 years, range 80-90 years). The cardiac pathology was calcific aortic stenosis (AS) in 40 cases, associated with coronary artery disease in 7 cases, mitral valve prolapse in 3 cases, coronary artery disease alone in 6 cases [complicated by a post-infarction ventricular septal defect (VSD) in one patient] or associated with aortic regurgitation in 1 case, and degeneration of an aortic bioprosthetic valve in 1 case. Forty patients (78%) were in Stage III or IV or the NYHA Classification. There was no other major pathology associated with the cardiac disease. Aortic valve replacement (AVR) was carried out in 42 patients, with a bioprosthetic valve in 38 patients. This procedure was associated with coronary bypass surgery in 7 cases and carotid artery surgery in 1 case. A mitral bioprosthesis was implanted in 2 patients and mitral valvuloplasty was carried out in 1 patient. An isolated myocardial revascularisation procedure was performed in 5 cases; the VSD was closed in 1 case. The hospital mortality was 17.6 per cent (9 patients). All deaths were of cardiac origin. Eleven patients had no postoperative complications at all. The 3 year survival rate of those who survived surgery was 71 per cent. Of the current 31 survivors, 29 are in Stage I or II of the NYHA Classification. These results suggest that surgery can be offered to octogenarians with invalidating cardiac disease alone carrying a poor short term prognosis.

摘要

1980年1月至1988年6月期间,51例80岁以上患者在拉皮提医院接受了心脏直视手术(26名女性和25名男性;平均年龄82±2岁,范围80 - 90岁)。心脏病理情况为:40例为钙化性主动脉瓣狭窄(AS),其中7例合并冠状动脉疾病,3例为二尖瓣脱垂,6例为单纯冠状动脉疾病[1例合并心肌梗死后室间隔缺损(VSD)],1例合并主动脉瓣关闭不全,1例为主动脉生物瓣退变。40例患者(78%)处于纽约心脏协会(NYHA)心功能分级的III或IV级。不存在与心脏疾病相关的其他重大病理情况。42例患者接受了主动脉瓣置换术(AVR),其中38例植入生物瓣。该手术在7例中与冠状动脉搭桥手术同时进行,1例与颈动脉手术同时进行。2例患者植入二尖瓣生物瓣,1例患者接受二尖瓣成形术。5例患者进行了单纯心肌血运重建手术;1例患者的室间隔缺损得以闭合。医院死亡率为17.6%(9例患者)。所有死亡均由心脏原因导致。11例患者术后完全没有并发症。手术存活者的3年生存率为71%。在目前的31名存活者中,29例处于NYHA分级的I或II级。这些结果表明,对于仅患有导致功能丧失的心脏病且短期预后较差的八旬老人,可以考虑进行手术。

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