Lederman J S, Fitzpatrick T B, Sober A J
Arch Dermatol. 1984 Nov;120(11):1449-52.
Skin markings and pathologic findings in 105 patients with cutaneous melanoma were reviewed to determine relationship between clinical findings, pathologic findings, and prognosis. Lesions with decreased or absent markings are significantly thicker than those with increased or normal markings and therefore carry a worse prognosis. Loss of skin markings is a late sign of melanoma and should not be relied on as an aid in early diagnosis.
回顾了105例皮肤黑色素瘤患者的皮肤特征和病理结果，以确定临床特征、病理结果和预后之间的关系。皮肤特征减少或缺失的病变比那些皮肤特征增加或正常的病变明显更厚，因此预后更差。皮肤特征缺失是黑色素瘤的晚期征象，不应依赖它来辅助早期诊断。
