Stern R, Godbold J H, Chess Q, Kagen L J
Arch Intern Med. 1984 Nov;144(11):2185-9.
Electrocardiographic abnormalities were found in 25 (32.5%) of 77 patients with polymyositis. Left anterior hemiblock (13.0%) and right bundle-branch block (9.1%) were the most common abnormalities. No association could be found between these defects and clinical activity of polymyositis, severity of duration of disease, or degree of creatine kinase level elevation. Similarly, there was no association with age or the presence of certain clinical conditions such as rash or arthritis. In only two patients, both children, did an ECG abnormality improve with corticosteroid therapy. Three patients with heart block died suddenly. This study points up the need for continual close observation of patients with inflammatory muscle disease, even after apparent remission.
77例多发性肌炎患者中,25例(32.5%)存在心电图异常。左前分支阻滞(13.0%)和右束支传导阻滞(9.1%)是最常见的异常情况。这些缺陷与多发性肌炎的临床活动度、疾病严重程度或病程长短、肌酸激酶水平升高程度之间均未发现关联。同样,与年龄或某些临床症状如皮疹或关节炎的存在也没有关联。仅2例患者(均为儿童)的心电图异常在接受皮质类固醇治疗后有所改善。3例心脏传导阻滞患者突然死亡。本研究强调,即使在明显缓解后,也需要对炎性肌肉疾病患者持续进行密切观察。