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[可移植性詹森肉瘤、环磷酰胺和长春碱、丁酸梭菌M55治疗试验及短期高血糖对白化大鼠某些白细胞功能的影响]

[Modification of selected leukocyte functions in albino rats caused by the transplantable Jensen sarcoma and by therapeutic trials of cyclophosphamide and vinblastine, Clostridium butyricum M55 and short-term hyperglycemia].

作者信息

Hambsch K, Henke R, Ludewig R

出版信息

Arch Geschwulstforsch. 1984;54(5):369-76.

PMID:6497582
Abstract

A significant increase in leukocyte adhesion and agglomeration was observed in white rats with Jensen sarcoma. Glucose induced short-term hyperglycemia temporarily stimulated these leukocyte functions in healthy rats. This effect was not notably influenced by administration of tumorlyzing spores. In contrast administration of the cytostatic agents vinblastine and cyclophosphamide demonstrated dose-related inhibition of leukocyte agglomeration and adhesion.

摘要

在患有詹森肉瘤的白鼠中观察到白细胞黏附和聚集显著增加。葡萄糖诱导的短期高血糖症在健康大鼠中暂时刺激了这些白细胞功能。这种效应并未受到溶瘤孢子给药的显著影响。相比之下,细胞抑制剂长春碱和环磷酰胺的给药显示出与剂量相关的白细胞聚集和黏附抑制作用。

相似文献

1
[Modification of selected leukocyte functions in albino rats caused by the transplantable Jensen sarcoma and by therapeutic trials of cyclophosphamide and vinblastine, Clostridium butyricum M55 and short-term hyperglycemia].[可移植性詹森肉瘤、环磷酰胺和长春碱、丁酸梭菌M55治疗试验及短期高血糖对白化大鼠某些白细胞功能的影响]
Arch Geschwulstforsch. 1984;54(5):369-76.
2
[Therapeutic experiments with spores of strain Clostridium butyricum and Cyclophosphamide in Jensen sarcoma, Walker carcinoma, and DS carcinosarcoma of the rat (author's transl)].
Arch Geschwulstforsch. 1974;44(1):65-9.
3
[Therapeutic attempt with clostridium butyricum spores and cyclophosphamide in Jensen's sarcoma of the rat].[用丁酸梭菌孢子和环磷酰胺对大鼠詹森肉瘤进行治疗的尝试]
Arch Geschwulstforsch. 1972;40(4):335-41.
4
[Treatment experiments with glucose-induced hyperglycaemia plus Clostridium-spores on the Jensen sarcoma of rats].[葡萄糖诱导的高血糖症联合梭状芽孢杆菌孢子对大鼠詹森肉瘤的治疗实验]
Arch Geschwulstforsch. 1982;52(4):267-73.
5
[Morphological studies on Jensen sarcoma in the rat under artificial short-term hyperglycemia].[人工短期高血糖状态下大鼠詹森肉瘤的形态学研究]
Arch Geschwulstforsch. 1984;54(6):471-4.
6
[Action of clostridial spores on transplantation tumors in alloxan-diabetic rats (author's transl)].
Arch Geschwulstforsch. 1975;45(8):795-801.
7
[The macrophage adherence inhibition test in Wistar rats bearing Jensen tumors. II. Macrophage adherence inhibition test after intravenous administration of spores of the CNRZ 528 strain of Clostridium butyricum and incubation with clostridial antigens].
Arch Geschwulstforsch. 1984;54(1):25-32.
8
[Behaviour of clostridial antibodies in rats with transplantable tumours under therapy by cyclophosphamide (author's transl)].
Arch Geschwulstforsch. 1974;44(2):103-5.
9
[Combined use of metronidazole and short-term hyperglycemia during radiation therapy of tumors in rats].[大鼠肿瘤放射治疗期间甲硝唑与短期高血糖的联合应用]
Radiobiologiia. 1985 May-Jun;25(3):333-7.
10
Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion.高葡萄糖浓度和高血糖以一种依赖核因子-κB的方式增强白细胞与内皮细胞的相互作用。
J Clin Invest. 1998 May 1;101(9):1905-15. doi: 10.1172/JCI656.