Chlumská A
Cesk Patol. 1984 Aug;20(3):161-9.
A lesion of small bile ducts wall in 6 women suffering from primary biliary cirrhosis (stage II, III, IV) included unspecific and progressive epithelial changes (increase of cytoskeleton, filaments, many phagosomes, basement membrane reduplication). Besides in stage II of the disease and in one case of cirrhosis, there were dense deposits in widened basement membrane and periductal macrophages which reminded of the bile. Some biliary canaliculi were dilated in all the cases and their microvilli were partly lost or swollen.
6例原发性胆汁性肝硬化（II期、III期、IV期）女性患者的小胆管壁病变包括非特异性进行性上皮变化（细胞骨架、细丝增加，大量吞噬体，基底膜重复）。此外，在疾病II期及1例肝硬化病例中，增厚的基底膜和导管周围巨噬细胞中有致密沉积物，类似胆汁。所有病例中均有一些胆小管扩张，其微绒毛部分缺失或肿胀。
