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地高辛免疫测定法可靠吗？

Are immunoassays for digoxin reliable?

作者信息

Soldin S J, Papanastasiou-Diamandi A, Heyes J, Lingwood C, Olley P

出版信息

Clin Biochem. 1984 Oct;17(5):317-20. doi: 10.1016/s0009-9120(84)90637-4.

DOI:10.1016/s0009-9120(84)90637-4
PMID:6499162
Abstract

The specificity of radioimmunoassay and fluorescence polarization immunoassay procedures for the measurement of digoxin has been assessed. Many steroids and lipids have been found to interfere and give false positive results for digoxin under the conditions of the study. Caution is recommended in the interpretation of digoxin measurements made by immunoassay procedures.

摘要

已对放射免疫分析和荧光偏振免疫分析程序在测定地高辛时的特异性进行了评估。在该研究条件下，发现许多类固醇和脂质会产生干扰并导致地高辛检测出现假阳性结果。建议在解释通过免疫分析程序进行的地高辛测量结果时谨慎行事。

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