Andrysek O, Bláhová E, Gregora V
Czech Med. 1984;7(3):161-6.
On the basis of an experimental model of the Lewis lung carcinoma a possibility was checked of obtaining basic kinetic data about the individual proliferation of tumour cells by a method of measuring the incorporation of labelles 125I 5-iodo-2-deoxyuridine intratumorously with a subsequent measurement of the retained activity in the tumour. These activity, which resides in the tumour for a time longer than 24 hours depends on the fraction of cells, that in the synthetic part of the cell cycle at the time of the injection.
基于Lewis肺癌实验模型，通过瘤内注射放射性标记物125I 5-碘-2-脱氧尿苷，随后测量肿瘤中保留的活性，检验了获取肿瘤细胞个体增殖基本动力学数据的可能性。这些在肿瘤中停留超过24小时的活性取决于注射时处于细胞周期合成期的细胞比例。
