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丹麦家族性结肠息肉病患者行结肠切除术后回肠直肠吻合术发生直肠癌的风险。

The risk of developing rectal cancer after colectomy and ileorectal anastomosis in Danish patients with polyposis coli.

作者信息

Bülow S

出版信息

Dis Colon Rectum. 1984 Nov;27(11):726-9. doi: 10.1007/BF02554599.

Abstract

Fifty-eight Danish polyposis patients had been treated with colectomy and ileorectal anastomosis by the end of 1982. Three of these patients developed rectal cancer despite regular proctoscopic control, but one was probably an overlooked synchronous cancer. The cumulative risk at five and ten years after operation (actuarial method) was 3.5 and 13.3 per cent (95 per cent confidence limits 0-10.3 and 0-70.3 per cent, respectively), which seem to be acceptably low figures. This study supports the assumption that colectomy and ileorectal anastomosis is still the operation of choice in polyposis patients without rectal cancer.

摘要

到1982年底,58名丹麦息肉病患者接受了结肠切除术和回肠直肠吻合术治疗。尽管进行了定期直肠镜检查,这些患者中有3人发生了直肠癌,但其中1例可能是被漏诊的同时性癌。术后5年和10年的累积风险(精算方法)分别为3.5%和13.3%(95%置信区间分别为0 - 10.3%和0 - 70.3%),这似乎是可以接受的低数值。本研究支持这样一种假设,即对于无直肠癌的息肉病患者,结肠切除术和回肠直肠吻合术仍是首选手术方式。

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