Shevchuk I N, Lopp A Kh
Eksp Onkol. 1984;6(1):22-4.
A mathematical method for the study of benzo(a)pyrene (BP) penetration into the skin of nude mice was elaborated and supported by the experimental data. BP, whose concentration was measured by its fluorescence intensity, was applied to the skin using a "dry" technique. The effect of certain phenols and products of oxybenzene oxidation was studied. It was found that only butylated hydroxytoluene inhibits essentially the rate of BP metabolism.
阐述了一种研究苯并(a)芘（BP）渗透裸鼠皮肤的数学方法，并得到了实验数据的支持。通过荧光强度测量其浓度的BP，采用“干燥”技术涂抹于皮肤上。研究了某些酚类和苯氧化产物的作用。发现只有丁基化羟基甲苯能基本抑制BP的代谢速率。
