Mosienko V S, Kuz'menko A P, Rikberg A B, Trushina V A
Eksp Onkol. 1984;6(3):55-7.
The effect of the primary tumour cryodestruction on a degree of metastatic spreading in the lungs was investigated in experiments with C57B1/6 mice with Lewis carcinoma of the lungs. It is found that after the tumour cryosurgery there was a less quantity of metastases as compared with operated animals (surgical removal of the tumour or amputation of the limb with the tumour) or with untreated animals. A regular correlation is observed between the degree of metastatic spreading and the efficiency of the primary tumour treatment. The relapse after cryosurgery or surgical removal of the tumour led to an increase in the quantity of pulmonary metastases.
在患有Lewis肺癌的C57B1/6小鼠实验中，研究了原发性肿瘤冷冻破坏对肺转移扩散程度的影响。结果发现，与接受手术的动物（手术切除肿瘤或截肢肿瘤肢体）或未治疗的动物相比，肿瘤冷冻手术后转移灶数量较少。转移扩散程度与原发性肿瘤治疗效果之间存在一定的相关性。冷冻手术或手术切除肿瘤后的复发导致肺转移灶数量增加。
