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[骨髓细胞对软琼脂中粒细胞-巨噬细胞前体细胞克隆生长的影响]

[Effect of bone marrow cells on the clonal growth of granulocyte-macrophage precursors in a soft agar].

作者信息

Vladimirskaia E B, Zamaraeva N V

出版信息

Eksp Onkol. 1984;6(4):46-9.

PMID:6499751
Abstract

The granulocyte-macrophage colony stimulating effect of bone marrow cells is shown to be less intensive than the stimulating effect of feeding leukocytes. It is supposed that these two stimulating substances activate different progenitor populations. Stimulating effect of mixture consisting of leukocytes and bone marrow cells are very close to that of bone marrow cells alone. Leukemic bone marrow cells demonstrate the least colony stimulating ability.

摘要

骨髓细胞的粒细胞-巨噬细胞集落刺激作用比喂食白细胞的刺激作用强度要低。据推测,这两种刺激物质激活不同的祖细胞群体。由白细胞和骨髓细胞组成的混合物的刺激作用与单独的骨髓细胞非常接近。白血病骨髓细胞的集落刺激能力最低。

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