Chissov V I, Rusakov K G, Shchitkov K G, Igitov V I, Il'ina A I
Eksp Onkol. 1984;6(4):66-70.
The influence of local ischaemia on the tumor growth rate and the character of metastases of Walker's carcinosarcoma-256 (WCS-256) and carcinoma RS-1 was studied in 168 male rats of Wistar line. The authors observed the dependence between the quantity of tumour cells in peripheral blood both under normal conditions and under local ischaemia in the tumour area. The efficiency of the produced ischaemia was controlled by the polarographic methods. The local ischaemia decreases grafting of tumours, reduces the growth rate and formation of the regional and distant metastases and decreases the quantity of the tumour cells in the peripheral blood.
