Feneley M P, Gavaghan T P, Kuchar D, Thorburn C W, Baron D W, Morgan J J
Eur Heart J. 1984 Oct;5(10):806-13. doi: 10.1093/oxfordjournals.eurheartj.a061569.
The sensitivity of existing electrocardiographic (ECG) Q-wave criteria for inferior myocardial infarction (IMI) is poor. New criteria were developed after prospective analysis of the ECGs of 300 consecutive subjects undergoing cardiac catheterization (group 1). These criteria were then prospectively tested in a second group of 300 consecutive subjects undergoing cardiac catheterization (group 2). Only patients with left bundle branch block were excluded from both groups. In each group, IMI subgroups were defined on the basis of angiographic inferior wall motion abnormalities associated with a 70% or greater stenosis of the supplying coronary artery. All subjects who did not satisfy these angiographic criteria were included in the non-IMI subgroups. The new ECG criteria defined in the group 1 subjects were: 'Q' waves in one or more of the ECG leads 2, 3, or a VF, where 'Q' waves are those at least 30 ms in duration (onset to nadir) or those with a Q:R ratio at least 1:4, provided the QRS amplitude is greater than or equal to 0.5 mV. The ECG pattern 'Q3qF', where 'q' waves are those not satisfying either of the above, is excluded from these criteria. When tested in the group 2 subjects, the proposed criteria were significantly (P less than 0.001) more sensitive (68%) than those of the New York Heart Association (28%), though less specific (84% versus 97%, P less than 0.001). Of 300 ECGs analysed by two independent observers, disagreements as to the diagnosis by the proposed criteria were encountered in 19 cases (6%).
现有的心电图(ECG)下壁心肌梗死(IMI)Q波标准敏感性较差。在对300例连续接受心脏导管检查的受试者(第1组)的心电图进行前瞻性分析后制定了新的标准。然后在另一组300例连续接受心脏导管检查的受试者(第2组)中对这些标准进行前瞻性测试。两组均仅排除左束支传导阻滞患者。在每组中,IMI亚组是根据与供应冠状动脉70%或更高狭窄相关的血管造影下壁运动异常来定义的。所有不满足这些血管造影标准的受试者被纳入非IMI亚组。在第1组受试者中定义的新ECG标准为:心电图导联Ⅱ、Ⅲ或aVF中的一个或多个出现“Q”波,其中“Q”波持续时间至少30毫秒(起始至最低点)或Q:R比值至少为1:4,前提是QRS波幅大于或等于0.5毫伏。这些标准排除了“Q3qF”心电图模式,其中“q”波不满足上述任何一项。在第2组受试者中进行测试时,所提出的标准敏感性显著更高(68%,P<0.001),高于纽约心脏协会的标准(28%),尽管特异性较低(分别为84%和97%,P<0.001)。在由两名独立观察者分析的300份心电图中,对于所提出标准的诊断存在分歧的有19例(6%)。