Bode M P, Bode H R
Dev Biol. 1984 Dec;106(2):315-25. doi: 10.1016/0012-1606(84)90230-6.
Excised pieces of hydra body tissue of varying size and shape regenerate into cylinders with a head and foot at opposite ends. The numbers of cells along the axial and circumferential dimensions were determined before, during, and after regeneration. The main process in shaping the excised tissue into a body column was found to be a rearrangement of the cells. When regenerates of different size were measured, the proportions of the body columns were found to vary, such that the smaller the animal the squatter the body column was. The presence of the head in regenerates was necessary for the formation or maintenance of the cylindrical shape, while the size of the head determined the proportions of the cylinder. The formation of a gradient of adhesivity induced by the developing head is suggested as the basis for the rearrangement of the cells into the cylindrical form.
切除的不同大小和形状的水螅身体组织片段会再生为两端分别有头和足的圆柱体。在再生之前、期间和之后，测定了沿轴向和圆周方向的细胞数量。发现将切除的组织塑造成身体柱的主要过程是细胞重排。当测量不同大小的再生体时，发现身体柱的比例各不相同，即动物越小，身体柱越矮胖。再生体中头部的存在对于圆柱体形状的形成或维持是必要的，而头部的大小决定了圆柱体的比例。由发育中的头部诱导形成的粘附性梯度被认为是细胞重排形成圆柱形的基础。
