Marchini A, Bertoli L V, Bozzi L B, Ciampalini G, Riva S
G Ital Cardiol. 1984 Aug;14(8):565-9.
We have assessed the prognostic significance of ST segment depression in the anterior precordial leads in patients with an acute inferior infarction. Eighty-four patients with ST segment depression greater than or equal to 1 mm in at least 2 chest leads (Group A) and 82 patients without ST depression (Group B), all admitted to the hospital within 24 hours from the onset of an acute inferior myocardial infarction, were evaluated. Patients with an old infarction, those with intraventricular conduction abnormalities or other causes that could modify the ST segment were excluded from the study. The number of patients affected by complications during the hospital stay was significantly higher in group A (54 patients of group A vs 27 of group B, p less than 0,001). Death, left ventricular failure, ventricular arrhythmias were considerably higher in group A. Moreover we observed that the persistence of the ST segment depression for more than 24 hours identified a subgroup of patients with a very strong risk of complications, particularly death and left ventricular failure. The follow up after 3-6 months, however, did not show any significant difference in both groups. In conclusion, from our study it appears that patients with an inferior infarction precordial ST segment depression have a graver prognosis in the acute phase while their mid-term fate does not seem to be influenced by the presence of this electrocardiographic abnormality.
我们评估了急性下壁心肌梗死患者胸前导联ST段压低的预后意义。对84例至少2个胸导联ST段压低≥1mm的患者(A组)和82例无ST段压低的患者(B组)进行了评估,所有患者均在急性下壁心肌梗死发病后24小时内入院。研究排除了有陈旧性心肌梗死、室内传导异常或其他可能改变ST段的病因的患者。住院期间A组并发症患者数量显著高于B组(A组54例,B组27例,p<0.001)。A组的死亡、左心室衰竭、室性心律失常发生率明显更高。此外,我们观察到ST段压低持续超过24小时的患者亚组发生并发症的风险非常高,尤其是死亡和左心室衰竭。然而,3至6个月后的随访显示两组之间无任何显著差异。总之,从我们的研究来看,下壁心肌梗死合并胸前导联ST段压低的患者在急性期预后较差,而中期预后似乎不受这种心电图异常的影响。