大鼠神经系统及相关器官和/或组织的自发性肿瘤

Spontaneous tumors of the nervous system and associated organs and/or tissues in rats.

作者信息

Maekawa A, Onodera H, Tanigawa H, Furuta K, Takahashi M, Kurokawa Y, Kokubo T, Ogiu T, Uchida O, Kobayashi K

出版信息

Gan. 1984 Sep;75(9):784-91.

Abstract

Spontaneous tumors of the nervous system and associated organs and/or tissues in 346 male and 346 female F344/DuCrj rats and 200 male and 177 female Slc:Wistar rats were examined. The main neurogenic tumors observed were gliomas and neurinomas, which were detected in both strains of rats. Out of 7 gliomas, 6 were found in the brain and 1 in the spinal cord, and out of 4 neurinomas, 2 were in the trigeminal nerves and the other 2 were in the spinal nerves. In addition, other types of tumors (2 granular cell tumors in the brain, 1 pinealoma, 3 ganglioneuromas in the adrenal gland, 1 undifferentiated carcinoma in the nasal cavity and 1 chordoma in the posterior neck region) were observed.

摘要

对346只雄性和346只雌性F344/DuCrj大鼠以及200只雄性和177只雌性Slc:Wistar大鼠的神经系统及相关器官和/或组织的自发性肿瘤进行了检查。观察到的主要神经源性肿瘤为胶质瘤和神经鞘瘤，在两种品系的大鼠中均有发现。7例胶质瘤中，6例位于脑内，1例位于脊髓；4例神经鞘瘤中，2例位于三叉神经，另外2例位于脊神经。此外，还观察到其他类型的肿瘤（脑内2例颗粒细胞瘤、1例松果体瘤、肾上腺3例神经节神经瘤、鼻腔1例未分化癌和后颈部1例脊索瘤）。