Franĕk J, Libich J, Kubín V
Folia Microbiol (Praha). 1984;29(5):375-84. doi: 10.1007/BF02887765.
A survey based on both literary data and the authors own results, concerning the mechanisms of sIgA-mediated antibacterial immunity, is presented. Secretory IgA is characterized as a specific component of the immune system of mucous membranes, which can recognize harmful bacterial and distinguish them from indigenous microflora physiologically colonizing the mucous membranes, to fix them to the mucous membrane surface and to direct further factors, such as mucin, lysozyme, etc. (which form the effector component of the mucous membrane immunity system) for their final inactivation and neutralization.
本文基于文献数据和作者自身研究成果,对分泌型免疫球蛋白A(sIgA)介导的抗菌免疫机制进行了综述。分泌型免疫球蛋白A是黏膜免疫系统的一种特异性成分,它能够识别有害细菌,并将其与正常定植于黏膜的本土微生物区分开来,进而将这些有害细菌固定在黏膜表面,并引导诸如黏蛋白、溶菌酶等其他因子(这些因子构成了黏膜免疫系统的效应成分)对其进行最终的灭活和中和。