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用于评估阿尔茨海默病患者的痴呆评定量表的临床效用。

The clinical utility of the dementia rating scale for assessing Alzheimer patients.

作者信息

Vitaliano P P, Breen A R, Russo J, Albert M, Vitiello M V, Prinz P N

出版信息

J Chronic Dis. 1984;37(9-10):743-53. doi: 10.1016/0021-9681(84)90043-2.

DOI:10.1016/0021-9681(84)90043-2
PMID:6501546
Abstract

Community residing patients with mild (n = 18) or moderately severe (n = 16) Alzheimer's disease and controls (n = 23) were given Mattis' Dementia Rating Scale (DRS) and a brief measure of confrontation naming selected from the Boston Naming Test (BNT). The DRS was shown to be a reliable and clinically useful measure of mental status in patients with Alzheimer's disease. The DRS subscales and the BNT had excellent internal consistency reliabilities and the total DRS score (TDRS) was shown to be generally unrelated to gender and education. Among the dementia patients, performance on the TDRS was significantly associated with functional competence. The two dementia samples had similar profiles on the DRS and BNT, with the mild subjects performing significantly better than the moderately severe subjects on each measure. Extending the range of DRS subscales would improve this measure's utility as an evaluation instrument.

摘要

对社区中患有轻度(n = 18)或中度重度(n = 16)阿尔茨海默病的患者以及对照组(n = 23)进行了马蒂斯痴呆评定量表(DRS)测试,并从波士顿命名测试(BNT)中选取了一项简短的对答命名测试。结果表明,DRS是评估阿尔茨海默病患者精神状态的可靠且具有临床实用性的指标。DRS分量表和BNT具有出色的内部一致性信度,并且DRS总分(TDRS)总体上与性别和教育程度无关。在痴呆患者中,TDRS表现与功能能力显著相关。两个痴呆样本在DRS和BNT上具有相似的特征,轻度患者在各项测试中的表现均显著优于中度重度患者。扩展DRS分量表的范围将提高该量表作为评估工具的效用。

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