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医院及非医院尸检中终末期呼吸道感染及其他肺部病变的尸检影像学、组织学和细菌学研究。

Postmortem radiographic, histological and bacteriological studies of terminal respiratory infections and other pulmonary lesions in hospital and non-hospital necropsies.

作者信息

Pääkkö P, Särkioja T, Hirvonen J, Nurmi T, Lahti R, Sutinen S

出版信息

J Clin Pathol. 1984 Nov;37(11):1282-8. doi: 10.1136/jcp.37.11.1282.

Abstract

One lung from 109 unselected hospital and 43 unselected non-hospital necropsies was studied using postmortem radiography with histological verification. Signs of acute bacterial infection, including bronchiolitis or bronchopneumonia, were present in 42.2% of the hospital necropsies and infection was the immediate cause of death in 8.3%. There was only one case of incipient bronchopneumonia among the non-hospital necropsies. Emphysema was the most common other pulmonary lesion in both groups. Gram negative bacteria were found significantly more often in the bronchial mucus of lungs with any pulmonary lesion, particularly those with signs of bacterial infection, than in the bronchial mucus of morphologically normal lungs in both groups of patients. In addition, the frequency of infections was associated with length of stay in hospital. This may reflect the prevalence of Gram negative infections in hospitals.

摘要

对109例未经挑选的医院尸检和43例未经挑选的非医院尸检的一侧肺进行了研究,采用尸检后放射照相并经组织学验证。急性细菌感染的迹象,包括细支气管炎或支气管肺炎,在42.2%的医院尸检中存在,感染是8.3%的直接死亡原因。非医院尸检中仅有1例早期支气管肺炎病例。肺气肿是两组中最常见的其他肺部病变。在两组患者中,有任何肺部病变的肺支气管黏液中革兰氏阴性菌的检出率明显高于形态学正常肺的支气管黏液,尤其是有细菌感染迹象的肺。此外,感染频率与住院时间长短有关。这可能反映了医院中革兰氏阴性菌感染的流行情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b043/498999/7265135714f0/jclinpath00182-0084-a.jpg

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