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特应性皮炎患者管理的最新进展

Recent developments in the management of patients with atopic dermatitis.

作者信息

Rasmussen J E

出版信息

J Allergy Clin Immunol. 1984 Dec;74(6):771-6. doi: 10.1016/0091-6749(84)90176-3.

Abstract

Management of most patients with AD should be directed toward basic therapy--lubricants, moderate potency topical steroids, and antihistamines. Only the severe or unresponsive patient should be considered for management with some of the techniques that have been discussed previously. In part, this is because the addition of extra therapy will substantially decrease long-term compliance, increase the cost of medical care, and produce a dissatisfied patient. There are, however, definite situations in which dietary manipulation, topical and systemic antiseptics, dietary supplementation, and ultraviolet light may be useful. The uses of environmental control, biofeedback, and coal tar were not discussed but may also be useful in certain situations. Finally, all physicians should realize that Herpes simplex infection in patients with AD can be a serious and sometimes life-threatening problem. Rapid, accurate diagnosis is the key to effective management with the newer anti-viral agents.

摘要

大多数特应性皮炎患者的治疗应针对基础治疗——使用润滑剂、中效外用类固醇和抗组胺药。只有病情严重或对基础治疗无反应的患者才应考虑采用之前讨论过的一些治疗方法。部分原因在于,增加额外治疗会大幅降低长期依从性、增加医疗费用,并使患者不满。然而,在某些特定情况下,饮食调整、局部和全身使用抗菌剂、饮食补充以及紫外线可能会有帮助。文中未讨论环境控制、生物反馈和煤焦油的用途,但在某些情况下它们可能也有用。最后,所有医生都应认识到,特应性皮炎患者的单纯疱疹感染可能是一个严重且有时会危及生命的问题。快速、准确的诊断是使用新型抗病毒药物进行有效治疗的关键。

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