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吞咽困难作为甲状腺功能亢进症的主要表现

Dysphagia as a primary manifestation of hyperthyroidism.

作者信息

Branski D, Levy J, Globus M, Aviad I, Keren A, Chowers I

出版信息

J Clin Gastroenterol. 1984 Oct;6(5):437-40. doi: 10.1097/00004836-198410000-00009.

DOI:10.1097/00004836-198410000-00009
PMID:6501830
Abstract

A 69-year old woman suffered from severe dysphagia, abdominal pain, and weight loss. The dysphagia was accompanied by nasal speech, nasal regurgitation of food, weakness, and wasting of the proximal muscles of the upper and lower girdles. Laboratory data revealed T3 sephadex uptake 65.2%; T4 15.1 mcg%; and T3 250 ng%. Treatment with antithyroid medication reversed the manifestation of all the symptoms, including dysphagia. Cine-studies revealed esophageal motor dysfunction as the cause of the dysphagia. Hyperthyroidism is a rare, but treatable cause of unexplained dysphagia.

摘要

一名69岁女性患有严重吞咽困难、腹痛和体重减轻。吞咽困难伴有鼻音、食物鼻反流、虚弱以及上下肢带近端肌肉萎缩。实验室检查数据显示T3葡聚糖摄取率为65.2%;T4为15.1微克%;T3为250纳克%。抗甲状腺药物治疗使所有症状包括吞咽困难的表现得到缓解。动态造影研究显示食管运动功能障碍是吞咽困难的原因。甲状腺功能亢进是不明原因吞咽困难的一种罕见但可治疗的病因。

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1
Dysphagia as a primary manifestation of hyperthyroidism.吞咽困难作为甲状腺功能亢进症的主要表现
J Clin Gastroenterol. 1984 Oct;6(5):437-40. doi: 10.1097/00004836-198410000-00009.
2
Hyperthyroidism presenting as dysphagia.以吞咽困难为表现的甲状腺功能亢进症。
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[Dysphagia as the only clinical manifestation of an hyperthyroidism].
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Hyperthyroidism and myasthenia gravis with features of Eaton-Lambert syndrome.伴有伊顿-兰伯特综合征特征的甲状腺功能亢进症和重症肌无力。
Neurology. 1976 Sep;26(9):882-7. doi: 10.1212/wnl.26.9.882.
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[ORL manifestations of myasthenia gravis].[重症肌无力的耳鼻喉科表现]
Acta Otorrinolaringol Esp. 2000 Aug-Sep;51(6):549-51.
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The problem of dysphagia.吞咽困难问题。
Practitioner. 1976 Jun;216(1296):631-6.
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[Dysphagia as the sole manifestation of myasthenia gravis].[吞咽困难作为重症肌无力的唯一表现]
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Dysphagia as a primary manifestation of hyperthyroidism: a case report.
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Dysphagia as a manifestation of thyrotoxicosis: report of three cases and literature review.吞咽困难作为甲状腺毒症的一种表现:三例报告及文献综述
Dysphagia. 2004 Spring;19(2):120-4. doi: 10.1007/s00455-003-0510-z.

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Gastrointestinal manifestations of endocrine disease.内分泌疾病的胃肠道表现
World J Gastroenterol. 2006 May 28;12(20):3174-9. doi: 10.3748/wjg.v12.i20.3174.
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Dysphagia as a manifestation of thyrotoxicosis: report of three cases and literature review.吞咽困难作为甲状腺毒症的一种表现:三例报告及文献综述
Dysphagia. 2004 Spring;19(2):120-4. doi: 10.1007/s00455-003-0510-z.
5
Treatment of Oropharyngeal Dysphagia.
Curr Treat Options Gastroenterol. 2003 Aug;6(4):273-281. doi: 10.1007/s11938-003-0019-4.
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Neurogenic dysphagia: what is the cause when the cause is not obvious?神经源性吞咽困难:病因不明显时原因何在?
Dysphagia. 1994 Fall;9(4):245-55. doi: 10.1007/BF00301918.