由花生四烯酸代谢产物介导的辣根过氧化物酶对猫的降压作用。
Hypotensive effects in cats caused by horseradish peroxidase mediated by metabolites of arachidonic acid.
作者信息
Sjaastad O V, Blom A K, Haye R
出版信息
J Histochem Cytochem. 1984 Dec;32(12):1328-30. doi: 10.1177/32.12.6501865.
PMID:6501865
Abstract
Horseradish peroxidase (HRP) given intravenously was shown to possess a marked hypotensive effect in cats. The effect was not noticeably influenced by antihistamines. Indomethacin and acetylsalicylic acid completely blocked the hypotensive effect of HRP. It is concluded that the effect of HRP on blood pressure is due to stimulation of the synthesis of metabolites of arachidonic acid.
摘要
静脉注射的辣根过氧化物酶（HRP）在猫身上显示出显著的降压作用。抗组胺药对该作用没有明显影响。吲哚美辛和乙酰水杨酸完全阻断了HRP的降压作用。得出的结论是，HRP对血压的作用是由于刺激了花生四烯酸代谢产物的合成。
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