Damas J
C R Seances Soc Biol Fil. 1978;172(5):1025-8.
In the rat, diethylcarbamazine, imidazole and L 8027 do not modify the hypotensive activity of PGE2 and arachidonic acid. The formation of SRS-A from arachidonic acid does not compete with the synthesis of PG in the cardiovascular system of the rat. The thromboxane A2 does not participate in the hypotensive activity of arachidonic acid in the rat.
在大鼠中,乙胺嗪、咪唑和L 8027不会改变前列腺素E2和花生四烯酸的降压活性。花生四烯酸生成慢反应物质A的过程在大鼠心血管系统中不与前列腺素的合成竞争。血栓素A2不参与花生四烯酸在大鼠中的降压活性。