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十二指肠溃疡患者胃液和血清中抑制素样肽的研究。

Studies on inhibin-like peptide in gastric juice and serum of patients with duodenal ulcers.

作者信息

Shanbhag S A, Sheth A R, Nanivadekar S A, Sheth N A

出版信息

J Endocrinol. 1984 Dec;103(3):389-93. doi: 10.1677/joe.0.1030389.

Abstract

Immunoreactive inhibin-like material (ILM) was measured by radioimmunoassay in serum and gastric juice samples of 23 fasting normal men and 23 men with duodenal ulcers (DU). Concentrations of ILM in gastric juice and serum of patients with DU were significantly higher than those in normal men (P less than 0.01). A strong positive correlation (r = 0.894) was observed between pH and ILM levels in gastric juice of normal men but not in patients with DU. Inhibin-like material in the gastric juice had a chromatographic profile similar to that of human seminal plasma.

摘要

采用放射免疫分析法测定了23名空腹正常男性和23名十二指肠溃疡(DU)男性患者血清及胃液样本中的免疫反应性抑制素样物质(ILM)。DU患者胃液和血清中的ILM浓度显著高于正常男性(P<0.01)。正常男性胃液中pH值与ILM水平之间观察到强正相关(r = 0.894),而DU患者未观察到这种相关性。胃液中的抑制素样物质具有与人精浆相似的色谱图。

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