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鞍上生殖细胞瘤根治性放射治疗后出现多发梭形颅内动脉瘤。病例报告。

Multiple fusiform intracranial aneurysms following curative radiation therapy for suprasellar germinoma. Case report.

作者信息

Azzarelli B, Moore J, Gilmor R, Muller J, Edwards M, Mealey J

出版信息

J Neurosurg. 1984 Dec;61(6):1141-5. doi: 10.3171/jns.1984.61.6.1141.

DOI:10.3171/jns.1984.61.6.1141
PMID:6502244
Abstract

A 17-year-old girl died from the rupture of a large fusiform aneurysm of the terminal internal carotid artery. Autopsy revealed three other fusiform aneurysms originating from major cerebral arteries clearly within the ports of previously administered telecobalt radiation therapy. Five years prior to her death, a suprasellar germinoma was partially removed and the area was treated by radiation therapy via three ports. The original arteriograms showed a normal vascular tree. Repeat arteriograms, 3 years and 8 months before her death, demonstrated the aneurysms. The development of aneurysms following radiation damage of the arteries has been reported previously, but not in intracranial vessels.

摘要

一名17岁女孩死于颈内动脉终末段大型梭形动脉瘤破裂。尸检发现另外三个梭形动脉瘤起源于大脑主要动脉,明显位于先前进行钴远距离放射治疗的照射野内。在她去世前五年,鞍上生殖细胞瘤被部分切除,该区域通过三个照射野接受了放射治疗。最初的血管造影显示血管树正常。在她去世前3年8个月的重复血管造影显示了动脉瘤。动脉受辐射损伤后动脉瘤的形成此前已有报道,但颅内血管未见报道。

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