全身血管对颅内压升高的反应。3. 单次气囊充气对颅内压和体循环的影响。
Systemic vascular responses to increased intracranial pressure. 3. Effects of individual balloon inflations on intracranial pressure and the systemic circulation.
作者信息
Fitch W, McDowall D G, Paterson G M, Hain W R
出版信息
J Neurol Neurosurg Psychiatry. 1978 Apr;41(4):340-4. doi: 10.1136/jnnp.41.4.340.
Abstract
The effects of discrete increases in the volume of an artificial space-occupying lesion on intracranial pressures and the systemic circulation were studied in six anaesthetised and artificially ventilated dogs. Each increase in volume, accompanied by an increase in supratentorial intracranial pressure, a decrease in supratentorial perfusion pressure, and an increase in transtentorial pressure gradient, induced alterations in the systemic circulation. There were a decrease in heart rate, marked alterations in the arrhythmia index, and increases in stroke volume and systemic vascular resistance. A period of transient systemic hypertension was noted to accompany each discrete increase in intracranial pressure.
摘要
在六只麻醉并进行人工通气的狗身上，研究了人工占位性病变体积的离散性增加对颅内压和体循环的影响。每次体积增加，伴随着幕上颅内压升高、幕上灌注压降低以及幕上下压力梯度增加，都会引起体循环的改变。心率下降，心律失常指数有明显改变，每搏输出量和体循环血管阻力增加。注意到每次颅内压离散性增加都伴有一段短暂的全身性高血压。
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Dynamic axial brain-stem distortion as a mechanism explaining the cardiorespiratory changes in increased intracranial pressure.动态性轴位脑干扭曲作为解释颅内压升高时心肺变化的一种机制。
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J Neurol Neurosurg Psychiatry. 1973 Apr;36(2):161-70. doi: 10.1136/jnnp.36.2.161.
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7
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