[Radioimmunoassay in the evaluation of the hormonal state of patients with malignant tumors of the female genitalia].

Using a radioimmunoassay of hormones, disorders in the system of hormonal relations were revealed in 210 patients with malignant ovarian and corpus uteri tumors and correlated with a clinical course of disease. The recovery of the hormonal balance can serve an objective criterion for the evaluation of therapeutic efficacy and for a search for new antitumor drugs and means of correction of the disturbed feedback between hypophyseal and ovarian functions as one of the main factors of the pathogenesis of malignant ovarian and corpus uteri tumors. The author describes the importance of radionuclide methods in vitro for an all-round control over changes in the respective components of the neuroendocrine system in treatment of dyshormonal tumors and possibilities of their use in screenings of the hormonal status.