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[The effect of exogenous tRNA from different sources on the biosynthesis of milk proteins].

作者信息

Turkovskaia G V, Starodub N F

出版信息

Mol Biol (Mosk). 1984 Sep-Oct;18(5):1380-4.

PMID:6504040
Abstract

The tRNA dependent cell--free protein--synthesizing system from rabbit differentiated mammary gland has been obtained. The level of protein synthesis including caseins was found to be much higher in the presence of homologous tRNA in comparison with tRNAs from non-differentiated mammary gland, liver, brewer's yeast. The efficiency of translation was shown to depend on the tRNA pool quantitative balance. The addition of tRNA to mammary gland explants causes stimulation of casein synthesis. The level of this stimulation depends on both the origin of tRNA and physiological state of the gland. It is concluded that the functional adaptation of tRNA is a regulatory link in specific protein biosynthesis at the translation level.

摘要

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