金属硫蛋白在整个细胞周期中的可诱导性。
Inducibility of metallothionein throughout the cell cycle.
作者信息
Tobey R A, Seagrave J
出版信息
Mol Cell Biol. 1984 Oct;4(10):2243-5. doi: 10.1128/mcb.4.10.2243-2245.1984.
Abstract
Synchronized Chinese hamster cells were induced with ZnCl2 at multiple stages of the cell cycle and labeled with [35S]cysteine, and the 35S-labeled proteins were isolated and separated into metallothionein and nonmetallothionein fractions. Metallothionein was found to be inducible in all stages of the cell cycle and in G1-arrested cells.
摘要
用氯化锌在细胞周期的多个阶段诱导同步化的中国仓鼠细胞，并用[35S]半胱氨酸进行标记，然后分离35S标记的蛋白质，并将其分为金属硫蛋白和非金属硫蛋白组分。结果发现，金属硫蛋白在细胞周期的所有阶段以及G1期停滞的细胞中均可诱导产生。
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