Gez E, Sulkes A
Oncology. 1984;41(6):399-402. doi: 10.1159/000225863.
A 67-year-old patient with breast carcinoma on treatment with aminoglutethimide (AG) developed profound leukopenia and sepsis. WBC count recovered within 1 week and the drug was renewed without further complications. The hematological toxicity of AG is reviewed. Detailed descriptions of this side effect of AG are usually lacking in most published series. It appears though that blood dyscrasia due to AG occurs rarely and is promptly reversible upon discontinuation of the drug, but renewal of its administration is not always possible.
一名67岁的乳腺癌患者在接受氨鲁米特（AG）治疗时出现了严重的白细胞减少症和败血症。白细胞计数在1周内恢复，且再次使用该药物未出现进一步并发症。对AG的血液学毒性进行了综述。大多数已发表的系列报道中通常缺乏对AG这种副作用的详细描述。然而，AG引起的血液恶病质似乎很少发生，停药后可迅速逆转，但并非总能再次使用该药物。
