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[超声和X射线照射后实体艾氏瘤有丝分裂活性及病理性有丝分裂频率的动态变化]

[Dynamics of mitotic activity and frequency of pathologic mitoses in solid Ehrlich tumor after exposure to ultrasound and x-rays].

作者信息

Smirnov R V, Pyshkina O V

出版信息

Radiobiologiia. 1984 Sep-Oct;24(5):662-6.

PMID:6505159
Abstract

The dynamics of mitotic activity and the frequency of pathologic mitoses and their spectrum in 180 mice bearing Ehrlich solid tumors were studied after exposure to X-rays (XR) (5.6 Gy), ultrasound (US) (2W/cm2, for 5 min) or the combined exposure to both agents delivered in a different sequence. The harmful effect of the above-mentioned agents diminished when they were delivered in the following order: US+XR, XR+US, XR, and US. After the combined treatment the spectrum of the pathologic mitoses widened.

摘要

研究了180只携带艾氏实体瘤的小鼠在接受X射线(XR)(5.6 Gy)、超声(US)(2W/cm²,持续5分钟)照射或按不同顺序联合照射这两种因素后有丝分裂活动的动态变化、病理性有丝分裂的频率及其谱型。当按以下顺序给予上述因素时,其有害作用减弱:超声+X射线、X射线+超声、X射线、超声。联合治疗后病理性有丝分裂的谱型变宽。

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