Smirnov R V, Pyshkina O V
Radiobiologiia. 1984 Sep-Oct;24(5):662-6.
The dynamics of mitotic activity and the frequency of pathologic mitoses and their spectrum in 180 mice bearing Ehrlich solid tumors were studied after exposure to X-rays (XR) (5.6 Gy), ultrasound (US) (2W/cm2, for 5 min) or the combined exposure to both agents delivered in a different sequence. The harmful effect of the above-mentioned agents diminished when they were delivered in the following order: US+XR, XR+US, XR, and US. After the combined treatment the spectrum of the pathologic mitoses widened.
研究了180只携带艾氏实体瘤的小鼠在接受X射线(XR)(5.6 Gy)、超声(US)(2W/cm²,持续5分钟)照射或按不同顺序联合照射这两种因素后有丝分裂活动的动态变化、病理性有丝分裂的频率及其谱型。当按以下顺序给予上述因素时,其有害作用减弱:超声+X射线、X射线+超声、X射线、超声。联合治疗后病理性有丝分裂的谱型变宽。