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[单纯性脊柱囊尾蚴病。关于脑脊液的笔记]

[Pure spinal cysticercosis. Note on the cerebrospinal fluid].

作者信息

Carydakis C, Baulac M, Laplane D, Schuller E, Philippon J

出版信息

Rev Neurol (Paris). 1984;140(10):590-3.

PMID:6505487
Abstract

A patient from Benin experienced bilateral sciatic pain, followed by a progressive sensori-motor defect of the lower limbs. Five years after, he displayed symptoms and signs of a thoracic spinal cord compression, but no definite level could be determined. Myelography showed numerous intrathecal cysts from the cauda equina to the cervical cord. The diagnosis of cysticercosis was made by examination of the cysts removed after lumbar laminectomy. The search for another localisation of the parasite was negative. Repeated examination of cerebrospinal fluid (CSF) showed the presence of eosinophils, a high protein concentration, and a local synthesis of immunoglobulin G with an oligoclonal profile on electrophoresis. An accidental cyst punction revealed a fluid with protein migration in the alpha, beta and gamma ranges and a local synthesis of immunoglobulin A. Treatment with Praziquantel was uneffective.

摘要

一名来自贝宁的患者出现双侧坐骨神经痛,随后下肢出现进行性感觉运动缺陷。五年后,他出现胸段脊髓压迫的症状和体征,但无法确定明确的病变节段。脊髓造影显示从马尾到颈髓有大量鞘内囊肿。通过对腰椎椎板切除术后切除的囊肿进行检查,确诊为囊尾蚴病。未发现寄生虫的其他寄生部位。多次脑脊液(CSF)检查显示有嗜酸性粒细胞、高蛋白浓度,且电泳显示免疫球蛋白G呈寡克隆分布并有局部合成。一次偶然的囊肿穿刺显示囊液中蛋白质在α、β和γ范围内迁移,且有免疫球蛋白A的局部合成。吡喹酮治疗无效。

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