Yeo J D, Hales J R, Stabback S, Bradley S, Fawcett A A, Kearns R
Spine (Phila Pa 1976). 1984 Oct;9(7):676-80. doi: 10.1097/00007632-198410000-00004.
The effect of experimental trauma on the blood flow in the central (essentially gray matter) and peripheral (essentially white matter) regions of the sheep's spinal cord was studied using a radioactive microsphere technique. In seven out of eight animals, a progressive fall in blood flow occurred in both the peripheral and central regions of the cord within 2 hours following injury and remained reduced over the period of recording (up to 12 hours). Changes in local vascular resistance indicated that in approximately 60% of our animals, changes in arterial pressure alone contributed highly significantly to the decreased spinal blood flow. There remains the possibility that early therapeutic intervention could sustain neuronal function where local blood flow would otherwise be inadequate in the damaged spinal cord.
采用放射性微球技术研究了实验性创伤对绵羊脊髓中央（主要为灰质）和外周（主要为白质）区域血流的影响。在8只动物中的7只中，损伤后2小时内脊髓外周和中央区域的血流均呈进行性下降，且在记录期（长达12小时）内一直保持降低。局部血管阻力的变化表明，在我们大约60%的动物中，仅动脉压的变化就对脊髓血流减少有极显著影响。仍有可能的是，早期治疗干预可以维持神经元功能，而在受损脊髓中，否则局部血流将不足。
