Gonzalez M S, Alfonso B, Seckinger D, Padhye A A, Ajello L
Sabouraudia. 1984;22(5):427-32.
A 26-year-old woman from Grand Cayman Island with a 3-month history of a lump in the left breast was presumptively diagnosed as having a carcinoma. A segmental resection was attempted. Histologic examination of the biopsied tissue showed extensive granulomatous inflammation, necrosis, and septate, branched, dematiaceous hyphae in the intralobular ducts as well as in the surrounding tissues. When cultured on Sabouraud dextrose and brain heart infusion agars, the tissue yielded a slow-growing, downy, dematiaceous mould. Microscopically, it produced short, branched and unbranched chains of holoblastic conidia in acropetal manner from erect conidiophores that were characteristic of the genus Cladosporium. The isolate grew well at 36-37 degrees C, but failed to grow above 37 degrees C. It did not liquefy gelatin nor decompose casein, xanthine, hypoxanthine, or tyrosine, but did hydrolyze urea. Comparative studies with other pathogenic and saprophytic species of Cladosporium revealed that it represented an undescribed species. It is named Cladosporium devriesii, sp. nov.
一名来自大开曼岛的26岁女性，左乳房有一肿块，病史3个月，初步诊断为癌。尝试进行了部分切除术。活检组织的组织学检查显示广泛的肉芽肿性炎症、坏死，小叶内导管以及周围组织中有分隔、分支、暗色菌丝。该组织在沙氏葡萄糖琼脂和脑心浸液琼脂上培养时，产生一种生长缓慢、有绒毛、暗色的霉菌。显微镜下，它从直立的分生孢子梗以向顶方式产生短的、分支和不分支的全壁分生孢子链，这是枝孢属的特征。该分离株在36 - 37摄氏度生长良好，但在高于37摄氏度时不生长。它不液化明胶，也不分解酪蛋白、黄嘌呤、次黄嘌呤或酪氨酸，但能水解尿素。与枝孢属其他致病和腐生菌种的比较研究表明，它代表一个未描述的物种。它被命名为德弗里斯枝孢菌，新种。
