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[α-生育酚与高压氧对高胆固醇血症兔血浆脂质脂肪酸组成的影响]

[Effect of alpha-tocopherol and hyperbaric oxygenation on lipid fatty-acid composition of the plasma in hypercholesteremic rabbits].

作者信息

Kosukhin A B

出版信息

Vopr Med Khim. 1984 Jul-Aug;30(4):36-9.

PMID:6506583
Abstract

When simultaneous effect of alpha-tocopherol and hyperbaric oxygenation on fatty acid composition of lipids was studied in blood plasma of rabbits with experimental atherosclerosis, 3-5-fold increase in activity of lecithin-cholesterol acyl transferase was detected (P less than 0.05). At the same time, alterations in the linoleate/oleate ratio were found involving a decrease in phospholipids, free fatty acids and triglycerides as well as an increase cholesterol esters. Concentration of free cholesterol was decreased 1.5-fold.

摘要

在对实验性动脉粥样硬化家兔血浆脂质脂肪酸组成进行α-生育酚与高压氧联合作用研究时,发现卵磷脂胆固醇酰基转移酶活性增加了3至5倍(P小于0.05)。同时,发现亚油酸/油酸比值发生改变,包括磷脂、游离脂肪酸和甘油三酯减少,胆固醇酯增加。游离胆固醇浓度降低了1.5倍。

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