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[妊娠中毒症患者抗凝血酶III浓度的变化]

[Changes in antithrombin III concentration in gestosis patients].

作者信息

Huber H, Brehm R

出版信息

Z Geburtshilfe Perinatol. 1984 Sep-Oct;188(5):223-5.

PMID:6506835
Abstract

Antithrombin-(AT)-III-levels from 22 patients were determined at the day of delivery but also at the first and fifth day post partum. 7 patients had an AT-III-level in a pathologically low range. Furthermore we found a close correlation between the degree of seriousness of gestosis and AT-III-reduction as well as hypercoagulolability expressed in an elevated normotest. With two patients serious complications arised intra- and postoperatively. One patient got a coagulopathy during the sectio, the other patient developed in spite of heparin treatment a deep thrombosis in the leg vein. These women had the lowest AT-III-levels from all 22 patients. These results underline the importance of an AT-III-control, above all with surgical operations of gestose patients.

摘要

测定了22例患者分娩当天以及产后第1天和第5天的抗凝血酶(AT)-III水平。7例患者的AT-III水平处于病理低范围。此外,我们发现妊娠中毒症的严重程度与AT-III降低以及以升高的正常凝血试验所表示的高凝状态之间存在密切相关性。两名患者在手术中和术后出现了严重并发症。一名患者在剖宫产时发生了凝血病,另一名患者尽管接受了肝素治疗,但仍发生了腿部深静脉血栓形成。这些女性的AT-III水平在所有22例患者中是最低的。这些结果强调了控制AT-III的重要性,尤其是对于患有妊娠中毒症的患者进行手术时。

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1
[Changes in antithrombin III concentration in gestosis patients].[妊娠中毒症患者抗凝血酶III浓度的变化]
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