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[二甲基亚砜在多发性硬化症治疗中的应用]

[Dimexide (dimethylsulfoxide) in the treatment of multiple sclerosis].

作者信息

Zingerman L Ia

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1330-3.

PMID:6506978
Abstract

Thirty-four patients with multiple sclerosis were treated with dimexide. The use of the drug was found to be desirable, since it had a positive effect on immunity and antiallergic and reparative action on the injured tissues. The treatment proved most effective in patients with a remitting course of the disease. In patients with a rapidly progressive course, the improvement was unstable. No side-effects were observed. The beneficial therapeutic effect of dimexide may be explained by remyelinization, a reduction in the edema and neurodynamic improvement.

摘要

34例多发性硬化患者接受了二甲亚砜治疗。发现使用该药是可取的,因为它对免疫有积极作用,对受损组织有抗过敏和修复作用。该治疗在疾病缓解期的患者中证明最有效。在疾病快速进展期的患者中,改善情况不稳定。未观察到副作用。二甲亚砜有益的治疗效果可能通过髓鞘再生、水肿减轻和神经动力学改善来解释。

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