Madsen E B, Gilpin E, Slutsky R A, Ahnve S, Henning H, Ross J
Am Heart J. 1984 Dec;108(6):1431-6. doi: 10.1016/0002-8703(84)90688-4.
We evaluated 229 patients discharged after a definite acute myocardial infarction. Pulmonary venous congestion determined from chest x-ray films during the hospitalization and at discharge and the cardiothoracic ratio at discharge were compared to the left ventricular ejection fraction measured at discharge by a gated radionuclide technique. During hospitalization, pulmonary venous congestion was found on at least one x-ray frame in 94 patients (41%). At discharge 134 patients (59%) had abnormal ejection fraction (less than 0.51) and 35 had pulmonary venous congestion (15%). The sensitivity of the x-ray for detecting an abnormal ejection fraction was 20% when pulmonary venous congestion was observed on the discharge x-ray film (specificity 92% and predictive value 77%), 52% if pulmonary venous congestion was present on any x-ray film during the hospitalization (specificity 74% and predictive value 73%), and 47% if the cardiothoracic ratio was abnormal (greater than or equal to 0.50) on the discharge x-ray film (specificity and predictive value 66%). We conclude that an abnormal x-ray film at discharge or during the hospitalization will identify approximately one-half of the abnormal ejection fractions at the time of hospital discharge. Therefore, to reliably assess left ventricular function, either for prognostic or therapeutic purposes in the individual patient, a more direct measure of left ventricular function such as radionuclide angiography must be obtained.
我们评估了229例确诊为急性心肌梗死后出院的患者。将住院期间及出院时胸部X光片所确定的肺静脉淤血情况以及出院时的心胸比率与出院时通过门控放射性核素技术测得的左心室射血分数进行比较。住院期间,94例患者(41%)在至少一张X光片上发现有肺静脉淤血。出院时,134例患者(59%)射血分数异常(低于0.51),35例有肺静脉淤血(15%)。当出院时X光片上观察到肺静脉淤血时,X光检测异常射血分数的敏感性为20%(特异性92%,预测值77%);如果住院期间任何一张X光片上有肺静脉淤血,则敏感性为52%(特异性74%,预测值73%);如果出院时X光片上心胸比率异常(大于或等于0.50),则敏感性为47%(特异性和预测值66%)。我们得出结论,出院时或住院期间X光片异常可识别出院时约一半的异常射血分数。因此,为了在个体患者中可靠地评估左心室功能,无论是用于预后评估还是治疗目的,都必须采用更直接的左心室功能测量方法,如放射性核素血管造影。