Nair C K, Sudhakaran C, Aronow W S, Thomson W, Woodruff M P, Sketch M H
Am J Cardiol. 1984 Dec 1;54(10):1286-7. doi: 10.1016/s0002-9149(84)80082-x.
The clinical characteristics of 107 patients younger than 60 years with mitral anular calcium (MAC) were compared with those of 107 age- and sex-matched control subjects. The patients with MAC included 55 men and 52 women, mean age 51 years. The control group included 55 men and 52 women, mean age 51 years. Patients with MAC had a higher prevalence of cardiomegaly on chest x-ray (p less than 0.0001), left atrial and left ventricular enlargement by echocardiography (p less than 0.0001), precordial murmurs (p less than 0.0001), diabetes mellitus (p less than 0.0001), systemic hypertension (p less than 0.025) and total conduction defects on surface electrocardiograms (p less than 0.0001) compared with the age- and sex-matched control subjects. The mean serum phosphorus and product of serum calcium and phosphorus were higher in patients with MAC (p less than 0.0025) than in the control subjects. The prevalence of coronary heart disease, aortic stenosis and hypertrophic cardiomyopathy and the mean serum cholesterol, triglyceride, total protein, albumin, creatinine, alkaline phosphatase and calcium levels were not significantly different between patients with MAC and the control subjects.
将107例年龄小于60岁的二尖瓣环钙化（MAC）患者的临床特征与107例年龄和性别匹配的对照者进行比较。MAC患者包括55名男性和52名女性，平均年龄51岁。对照组包括55名男性和52名女性，平均年龄51岁。与年龄和性别匹配的对照者相比，MAC患者胸部X线显示心脏扩大的患病率更高（p<0.0001），超声心动图显示左心房和左心室扩大（p<0.0001），心前区杂音（p<0.0001），糖尿病（p<0.0001），系统性高血压（p<0.025）以及体表心电图显示完全性传导阻滞（p<0.0001）。MAC患者的血清磷均值以及血清钙和磷的乘积高于对照者（p<0.0025）。MAC患者与对照者之间冠心病、主动脉瓣狭窄和肥厚型心肌病的患病率以及血清胆固醇、甘油三酯、总蛋白、白蛋白、肌酐、碱性磷酸酶和钙水平无显著差异。
