Dykes D D, Mount M, Polesky H F
Am J Clin Pathol. 1984 Dec;82(6):722-5. doi: 10.1093/ajcp/82.6.722.
Isoelectric focusing of plasminogen (PLG) was tested on a Minnesota population of 2,187 white individuals and 451 paternity cases. A total of six different PLG allotypes were observed PLG1, PLG2, PLG3, PLGB, PLGD and PLGM. Observed gene frequencies predicted a probability P = 0.2 of excluding men who were falsely determined to be parents. The observed frequency of PLG exclusions among all exclusions detected in the study using a test battery of 14-16 genetic markers was similar to the expected value. PLG phenotyping proved to be a very useful genetic marker system in routine parentage testing.
在明尼苏达州的2187名白人个体和451例亲子鉴定案例的人群中，对纤溶酶原（PLG）进行了等电聚焦检测。共观察到六种不同的PLG别型，即PLG1、PLG2、PLG3、PLGB、PLGD和PLGM。观察到的基因频率预测，排除被错误判定为父母的男性的概率P = 0.2。在该研究中，使用包含14 - 16种遗传标记的检测组合检测到的所有排除案例中，PLG排除的观察频率与预期值相似。在常规亲子鉴定中，PLG表型分析被证明是一个非常有用的遗传标记系统。
