Van Deventer G M
Am J Med. 1984 Nov 19;77(5B):15-22.
Determining a course of long-term management for the patient with peptic ulcer disease requires an assessment of the severity of the disease, prior ulcer history (including complications, therapeutic intervention, and response to treatment), the predictors of the disease course, the degree of disability, and the available therapy (pharmacologic or surgical). A consideration of the predictors of the disease course that have been previously identified as useful in ulcer clinical trials (sex, age, acid secretory response, serum pepsinogen concentration, cigarette usage) and of ulcer-related disability (nutritional, emotional, job status) provides objective criteria to be entered into the long-term management decision.
确定消化性溃疡病患者的长期管理方案需要评估疾病的严重程度、既往溃疡病史（包括并发症、治疗干预及对治疗的反应）、疾病进程的预测因素、残疾程度以及可用的治疗方法（药物治疗或手术治疗）。考虑先前在溃疡临床试验中已确定为有用的疾病进程预测因素（性别、年龄、胃酸分泌反应、血清胃蛋白酶原浓度、吸烟情况）以及与溃疡相关的残疾情况（营养、情绪、工作状态），可为长期管理决策提供客观标准。
