Allgulander C, Borg S, Vikander B
Am J Psychiatry. 1984 Dec;141(12):1580-2. doi: 10.1176/ajp.141.12.1580.
The authors studied 50 of 55 patients originally hospitalized for primary sedative-hypnotic dependence 4-6 years after hospital discharge. Forty-two (84%) of the patients had resumed using sedative-hypnotics, 26 (52%) were abusing drugs at follow-up, and 21 (42%) had been readmitted for drug abuse. Three patients experienced delirious states and six experienced epileptic seizures associated with withdrawal. Physical signs of alcoholism had developed in 11 (22%); four (8%) had committed suicide. Social deterioration was noted in 24 patients. CAT scan results did not deviate from those found in a matched control sample.
作者对最初因原发性镇静催眠药依赖而住院的55名患者中的50名进行了出院4至6年后的研究。其中42名（84%）患者恢复使用了镇静催眠药，26名（52%）患者在随访时存在药物滥用情况，21名（42%）患者因药物滥用再次入院。3名患者出现谵妄状态，6名患者出现与戒断相关的癫痫发作。11名（22%）患者出现了酒精中毒的体征；4名（8%）患者自杀。24名患者出现了社会功能恶化。计算机断层扫描（CAT）结果与匹配的对照样本无异。
