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[抗焦虑药与老年受试者的记忆能力。关于硫必利与劳拉西泮的双盲研究]

[Anxiolytics and mnemonic ability of the aged subject. Apropos of a double-blind study between tiapride and lorazepam].

作者信息

Léger J M, Herrmann C, Malauzat D, Danot G, Lombertie E R

出版信息

Ann Med Psychol (Paris). 1984 May;142(5):696-702.

PMID:6508068
Abstract

Starting from a study of memory performances while prescription in double blind of lorazepam (2 mg/day) versus tiapride (100 mg/day), during ten days, to patients over sixty years of age, the authors try to analyse the links between anxiety, anxiolysis and attention and memory capacities. Results seem to indicate that beyond anxiolysis, these products could have an independent action over memory performances. Statistical trial of results show significantly that performances decrease under lorazepam and increase under tiapride.

摘要

作者对60岁以上患者进行了一项研究,在双盲条件下让患者服用劳拉西泮(2毫克/天)或硫必利(100毫克/天),持续十天,同时研究记忆表现,试图分析焦虑、抗焦虑作用与注意力及记忆能力之间的联系。结果似乎表明,除了抗焦虑作用外,这些药物对记忆表现可能有独立作用。对结果的统计学试验显著表明,服用劳拉西泮后表现下降,而服用硫必利后表现上升。

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