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对血浆碱性核糖核酸酶作为婴儿蛋白质营养状况指标的批判性评估。

A critical assessment of plasma alkaline ribonuclease as an indicator of protein nutritional status in infancy.

作者信息

Scott P H, Berger H M, Wharton B A

出版信息

Ann Clin Biochem. 1984 Sep;21 ( Pt 5):357-62. doi: 10.1177/000456328402100503.

DOI:10.1177/000456328402100503
PMID:6508206
Abstract

Plasma alkaline ribonuclease (RNase) was measured at birth and during infancy to assess its usefulness as an indicator of protein nutritional status. Cord blood enzyme activity did not indicate intra-uterine protein malnutrition in the less well-grown babies. Differences in enzyme activity were found which related to the quality of the dietary protein fed to both preterm and term light for gestational age babies. Higher activity on day 7 in those infants fed a predominantly curd protein formula suggested that this was less well utilised than a curd and whey protein formula. Serial enzyme measurements in four infants with metabolic disease showed how the enzyme activity altered in response to changes in the quantity of dietary protein. These results are critically discussed.

摘要

在出生时及婴儿期测定血浆碱性核糖核酸酶(RNase),以评估其作为蛋白质营养状况指标的实用性。脐血酶活性并未表明生长较差的婴儿存在宫内蛋白质营养不良。发现酶活性存在差异,这与喂养给早产儿和足月小样儿的膳食蛋白质质量有关。在第7天,那些主要喂食凝乳蛋白配方奶的婴儿酶活性较高,这表明该配方奶的利用率不如凝乳和乳清蛋白配方奶。对四名患有代谢疾病的婴儿进行的系列酶测量显示了酶活性如何随膳食蛋白量的变化而改变。对这些结果进行了批判性讨论。

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