Tigerstedt I, Turunen M T, Hästbacka J
Ann Clin Res. 1984;16(4):204-10.
Intracholedochal passage pressures (ICPP) were measured during halothane, enflurane and isoflurane anaesthesia as well as during anaesthesia without any volatile agent and in patients with a postoperative T-tube. There were no statistically significant differences in the mean ICPP between the study groups (altogether 49 patients). After i.v. fentanyl 0.1 mg a similar pressure increase (mean 0.5 kPa) was recorded in all anaesthetized groups as compared to a threefold increase (mean 1.6 kPa) in the postoperative group (p less than 0.001) with maximum at about 7 min in all groups. Intraoperative fentanyl did not cause surgically adverse effects i.e. false obstruction due to spasm in the operative cholangiography. It is concluded that all inhalation anaesthetics attenuate the ICPP response to fentanyl.
在氟烷、恩氟烷和异氟烷麻醉期间，以及在未使用任何挥发性麻醉剂的麻醉期间和术后带有T型管的患者中，测量了胆总管内通道压力（ICPP）。研究组（共49例患者）之间的平均ICPP无统计学显著差异。静脉注射0.1 mg芬太尼后，与术后组（平均1.6 kPa）增加三倍（平均0.5 kPa）相比，所有麻醉组均记录到类似的压力升高（平均0.5 kPa），所有组在约7分钟时达到最大值。术中使用芬太尼未引起手术不良反应，即术中胆管造影时因痉挛导致的假梗阻。得出的结论是，所有吸入性麻醉剂均会减弱ICPP对芬太尼的反应。
