McClimans C D, Selwyn B J, Forthofer R N, Severs R K
Arch Environ Health. 1984 Sep-Oct;39(5):331-8. doi: 10.1080/00039896.1984.10545859.
Records of 3006 employees of nine companies in southeast Texas screened by a local lung association during the years 1974-1975 were examined to assess the effect of smoking, age, and occupational and residential ambient air pollution exposure. The effects of smoking and occupational exposure were strong when tested against a respiratory morbidity response questionnaire considered to be diagnostic for early-stage bronchitis. Occupational exposure lost statistical significance after place of residence was controlled in the analysis. Smoking and age variables exhibited significant effects when the response variable was pulmonary function test results. The differences between questionnaire and pulmonary function test results may indicate early-stage vs. later-stage respiratory morbidity ascertainment. Agreement in classifying "abnormal" subjects with these two methods decreased with increasing levels of smoking.
1974年至1975年期间，得克萨斯州东南部九家公司的3006名员工接受了当地肺部协会的筛查，其记录被用于评估吸烟、年龄、职业和居住环境空气污染暴露的影响。当针对被认为可诊断早期支气管炎的呼吸道发病率调查问卷进行测试时，吸烟和职业暴露的影响显著。在分析中控制居住地点后，职业暴露失去了统计学意义。当反应变量为肺功能测试结果时，吸烟和年龄变量显示出显著影响。调查问卷和肺功能测试结果之间的差异可能表明早期与晚期呼吸道发病率的确定情况。随着吸烟水平的增加，用这两种方法对“异常”受试者进行分类的一致性降低。
