McKneally M F, Britton L W, Scott J R, Kausel H W
Ann Thorac Surg. 1984 Dec;38(6):606-10. doi: 10.1016/s0003-4975(10)62318-1.
Severe gastroesophageal reflux was found in 9 out of 18 infants with congenital esophageal atresia studied radiographically shortly after primary reconstruction. Pulmonary complications were recorded in 18 out of 32 similar patients in long-term follow-up. Strictures at the level of the anastomosis were detectable in 18 out of 32 patients; eleven strictures were severe enough to require dilation or surgical revision. These findings suggest that early evaluation for gastroesophageal reflux may be useful in management of infants with esophageal atresia. The precautions taken preoperatively to prevent complications of gastroesophageal reflux should be continued in the postoperative interval unless a competent lower esophageal sphincter is demonstrated.
在18例先天性食管闭锁患儿中，有9例在初次重建后不久经影像学检查发现严重胃食管反流。在32例类似患者的长期随访中，有18例出现肺部并发症。32例患者中有18例在吻合口水平可检测到狭窄；11处狭窄严重到需要扩张或手术修正。这些发现表明，对胃食管反流进行早期评估可能有助于食管闭锁患儿的治疗。除非证实存在功能正常的食管下括约肌，否则术前为预防胃食管反流并发症所采取的预防措施在术后应继续进行。
