大麦町犬肝脏中尿酸摄取缺陷。
Defect of uric acid uptake in Dalmatian dog liver.
作者信息
Giesecke D, Tiemeyer W
出版信息
Experientia. 1984 Dec 15;40(12):1415-6. doi: 10.1007/BF01951919.
PMID:6510499
Abstract
The uptake rate of uric acid into liver slices of the Dalmatian dog was found to be significantly lower compared with that in the beagle. Since there was no difference in the hepatic uricase activity between the two breeds, the abnormality of uric acid metabolism in the Dalmatian dog is considered to result from a defective hepatic transport system for uric acid.
摘要
研究发现，与比格犬相比，大麦町犬肝脏切片对尿酸的摄取率显著降低。由于两个品种的肝脏尿酸酶活性没有差异，因此认为大麦町犬尿酸代谢异常是由肝脏尿酸转运系统缺陷所致。
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